2026-05-13T16:18:34.766Z http://ezaposleni.singidunum.ac.rs/rest/sciNaucniRezultati/oai

ezaposleni.singidunum.ac.rs/rest/sciNaucniRezultati/oai:2:10050 2024-06-29T20:52:00Z 2

High-Altitude Pulmonary Edema in Women: A Scoping Review—UIAA Medical Commission Recommendations 2023 http://ezaposleni.singidunum.ac.rs/rest/sciNaucniRezultati/oai/record/2/10050 https://www.liebertpub.com/doi/10.1089/ham.2023.0054 J. Pichler Hefti D. Jean A. Rosier M. Derstine D. Hillebrandt L. Horakova L. Keyes K. Mateikaite - Pipiriene P. Paal M. Anđelković B. Beidleman S. Kriemler Pichler Hefti, Jacqueline, Dominique Jean, Alison Rosier, Mia Derstine, David Hillebrandt, Lenka Horakova, Linda E. Keyes, Kast_e Mateikait_e-Pipirien_ e, Peter Paal, Marija Andjelkovic, Beth Beidlemann, and Susi Kriemler. High-altitude pulmonary edema in women: a scoping review—UIAA Medical Commission Recommendations. High Alt Med Biol. 24:268–273, 2023. Background: High-altitude pulmonary edema (HAPE) can occur >2,500–3,000m asl and is a life-threatening medical condition. This scoping review aims to summarize the current data on sex differences in HAPE. Methods: The International Climbing and Mountaineering Federation (UIAA) Medical Commission convened an international author team to review women’s health issues at high altitude. Pertinent literature from PubMed and Cochrane was identified by keyword search combinations (including HAPE), with additional publications found by hand search. The primary search focus was for original articles that included minimum one woman and at least a rudimentary subgroup analysis. Results: The literature search yielded 7,165 articles, 416 of which were relevant for HAPE, and 7 of which were ultimately included here. Six were case series, consistently reporting a lower HAPE prevalence in women. The one retrospective case–control study reported male HAPE prevalence at 10/100,000 and female at 0.74/100,000. No studies were identified that directly compared sex differences in the prevalence of HAPE. No published data was found for topics other than epidemiology. Conclusions: Few studies and associated methodological limitations allow few conclusions to be drawn. Incidence of HAPE may be lower in women than in men. We speculate that besides physiological aspects, behavioral differences may contribute to this potential sex difference. article 10.1089/ham.2023.0054 24 4 268 273 1557-8682 HIGH ALTITUDE MEDICINE & BIOLOGY